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G-418 Sulfate Solution (50 mg/mL)

97,00 

(Cell-Culture Grade)

Overview

G-418 Sulfate Solution is an aqueous solution of G-418 sulfate at 50 mg/ mL. This antibiotic, isolated in 1974 from Micromonospora rhodorangea, belongs to the group of aminoglycoside antibiotics, It is widely used in molecular and cell biology experiments. Its mechanism of action is based on blocking polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. Resistance to G-418 is conferred by the neo gene, located on both transposons Tn5 and Tn601 (903). They have been included in some plasmids as selective genes.

 

For Research Use Only. Not for use in diagnostic procedures.

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