G-418 Sulfate Solution

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Cellular and Biochemical Assays

G-418 Sulfate Solution

(Cell-Culture Grade)

Overview

G-418 Sulfate Solution is an aqueous solution of G-418 sulfate at 50 mg/ mL. This antibiotic, isolated in 1974 from Micromonospora rhodorangea, belongs to the group of aminoglycoside antibiotics, It is widely used in molecular and cell biology experiments. Its mechanism of action is based on blocking polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. Resistance to G-418 is conferred by the neo gene, located on both transposons Tn5 and Tn601 (903). They have been included in some plasmids as selective genes.

For Research Use Only. Not for use in diagnostic procedures.

Cat. No.FormatConc. Price
TBR033410 mL50 mg/mL97 €

Prices excl. VAT plus shipping costs.

How to order?

  • CAS: 108321-42-2
  • Formula: C20H40N4O10 x 2H2SO4
  • MW: 692.71 g/mol
  • Sterile by filtration
  • 100% Potency
  • Activity 1,000μg/ mg
  • Endotoxin ≤10 EU/ mL
  • Selection of plant and mammalian cells genetically modified with NeoR plasmids.
  • Antibiotic action against to bacteria, yeast, higher plant, mammalian cells, protozoans, and helminths.
  • Inhibit poliovirus and rhinovirus 2A proteinases in vitro.
  • Shipped in: Shipped in blue ice. 
  • Storage: Store at -20°C.

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